2020

Impact of Tolerance to Fluconazole on Treatment Response in Candida albicans Bloodstream Infection

Levinson T, Dahan A, Novikov A, Paran Y, Berman J, and Ben‐Ami T. Mycoses. 2020 Sep 30; doi: 10.1111/myc.13191

Elevated Vacuolar Uptake of Fluorescently Labeled Antifungal Drug Caspofungin Predicts Echinocandin Resistance in Pathogenic Yeast.

Jaber QZ, Bibi M, Ksiezopolska E, Gabaldon T, Berman J, and Fridman M. ACS Central Science. 2020 Sep 9; doi: 10.1021/acscentsci.0c00813

Evaluation of Microsatellite Typing, ITS Sequencing, AFLP Fingerprinting, MALDI-TOF MS, and Fourier-Transform Infrared Spectroscopy Analysis of Candida auris.

Vatanshenassan M, Boekhout T, Mauder N, Robert V, Maier T, Meis JF, Berman J, Then E, Kostrzewa M, and Hagen F. Journal of Fungi. 2020 Aug 25; 6(3):146. doi: 10.3390/jof6030146

Identification of Essential Genes and Fluconazole Susceptibility Genes in Candida glabrata by Profiling Hermes Transposon Insertions

Gale AN, Sakhawala RM, Levitan A, Sharan R, Berman J, Timp W, and Cunningham KW. G: Genes, Genomes, Genetics. 2020 Aug 3. doi:10.1534/g3.120.401595

Combination of miconazole and domiphen bromide is fungicidal against biofilms of resistant Candida spp.

Tits J, Cools F, De Cremer K, De Brucker K, Berman J, Verbruggen K, Gevaert B, Cos P, Cammue BPA and Thevissen K. Antimicrobial Agents and Chemotherapy. 2020 July 20; doi:10.1128/AAC.01296-20

Comparing the Utility of in vivo Transposon Mutagenesis Approaches in Yeast Species to Infer Gene Essentiality.

Levitan A, Gale AN, Dallon EK, Kozan DW, Cunningham KW, Sharan R, and Berman J. Current Genetics. 2020 July 17; doi:10.1007/s00294-020-01096-6

Candida albicans Genetic Background Influences Mean and Heterogeneity of Drug Responses and Genome Stability During Evolution to Fluconazole.

Gertsein A and Berman J. mSphere. 2020 June 24; doi:10.1128/mSphere.00480-20

Peptide Self-Assembly is Linked to Antibacterial, but Not Antifungal, Activity of Histatin 5 Derivatives.

Schnaider L, Rosenberg A, Kreiser T, Kolusheva S, Gazit E and Berman J. mSphere. 2020 April 1; doi:10.1128/mSphere.00021-20

Drug Resistance and Tolerance in Fungi.

Berman J and Krysan DJ. Nat Rev Microbiol. 2020 February 11; 18:319-331. doi:10.1038/s41579-019-0322-2

Extracellular ATP Released from Candida albicans Activates Non-Peptidergic Neurons to Augment Host Defense.

Edwards T, Zhang S, Liu A, Cohen J, Zhou P, Mogavero S, Hube B, Berman J, Bougnoux M, Mathers A, Gaffen S, Albers KM, Koeber HR, Davis B, d'Enfert B and Kaplan DH. bioRxiv. 2020 January 28; doi:10.1101/2020.01.27.921049

2019

Anidulafungin Susceptibility Testing of Candida glabrata Isolates from Blood Cultures by the MALDI Biotyper Antibiotic (Antifungal) Susceptibility Test Rapid Assay

Vatanshenassan M, Arastehfar A, Boekhout T, Berman J, Lass-Flörl C, Sparbier K, and Kostrzewa M. American Society for Microbiology. 2019 August 23; doi:10.1128/AAC.00554-19

Chromatin Profiling of the Repetitive and Nonrepetitive Genomes of the Human Fungal Pathogen Candida albicans.

Price RJ, Weindling E, Berman J, and Buscaino A. mBio. 2019 July 23; doi:10.1128/mBio.01376-19

Predicting Microbial Growth in a Mixed Culture from Growth Curve Data.

Ram Y, Dellus-Gur E, Bibi M, Karkare K, Obolski U, Feldman MW, Cooper TF, Berman J, and Hadany L. Proceedings of the National Academy of Sciences USA. 2019 Jun 16; doi:10.1073/pnas.1902217116

Selection of Candida albicans Trisomy During Oropharyngeal Infection Results in a Commensal-Like Phenotype.

Forche A, Solis NV, Swidergall M, Thomas R, Guyer A, Beach A, Cromie GA,  Le GT, Lowell E, Pavelka N, Berman J, Dudley AM, Selmecki A, and Filler  SG. PLoS Genetics. 2019 May 15; doi:10.1371/journal.pgen.1008137

Aneuploidy Enables Cross-Adaptation to Unrelated Drugs.

Yang F, Teoh F, Tan ASM, Cao Y, Pavelka N, and Berman J. Molecular Biology and Evolution. 2019 Apr 27; doi:10.1093/molbev/msz104

Autonomously Replicating Linear Plasmids That Facilitate the Analysis of Replication Origin Function in Candida albicans.

Bijlani S, Thevandavakkam MA, Tsai HJ, and Berman J. mSphere. 2019 Mar 6; 4(2). doi:10.1128/mSphere.00103-19

Candida auris Identification and Rapid Antifungal Susceptibility Testing Against Echinocandins by MALDI-TOF MS

Vatanshenassan M, Boekhout T, Meis JF, Berman J, Chowdhary A, Ben-Ami R, Sparbier K, and Kostrzewa M. Front Cell Infect Microbiol. 2019 Feb 18; 9(20). doi:10.3389/fcimb.2019.00020

Dynamic Ploidy Changes Drive Fluconazole Resistance in Human Cryptococcal Meningitis.

Stone NRH, Rhodes J, Fisher MC, Mfinanga S, Kivuyo S, Rugemalila J,  Segal ES, Needleman L, Molloy SF, Kwon-Chung J, Harrison TS, Hope W,  Berman J, and Bicanic T. Journal of Clinical Investigation. 2019 Jan 28; doi:10.1172/JCI124516

2018

Genetic background influences heterogeneity of adaptive response  and genome stability during prolonged antifungal drug exposure in Candida albicans.

Gerstein AC, and Berman J. bioRxiv. 2018 December 3; doi:10.1101/360347

Gene Essentiality Analyzed by in vivo Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of Candida albicans.

Shtifman-Segal E, Gristenko V, Levitan A, Yadav B, Dror N, Steenwyk J,  Silberberg Y, Mielich K, Rokas A, Kunze R, Sharan R, Gow R, and Berman  J. mBio. 2018 Sept; 9:5. doi:10.1128/mBio.02048-18

Candida albicans Dispersed Cells Are Developmentally Distinct from Biofilm and Planktonic Cells.

Uppuluri P, Zaldivar MA, Anderson MZ, Dunn MJ, Berman J, Lopez-Ribot JL, and J Koehler. mBio. 2018 Aug 21;9(4). doi: 10.1128/mBio.01338-18

Living Bacteria in Thermoresponsive Gel for Treating Fungal Infections.

Orbach A, Corem-Salkmon E, Berman J, Nyska A, and Mizrahi B. Advanced Functional Materials. 2018 Aug 6;28(40). doi:10.1002/adfm.201801581

Antifungal Tolerance is a Subpopulation Effect Distinct from Resistance and is Associated with Persistent Candidemia.

Rosenberg A, Ene IV, Bibi M, Zakin S, Shtifman-Segal E, Ziv N, Dahan A, Colombo A L, Bennett R J, and Berman J. Nature Communications. 2018 Jun 25; 9:2470. doi:10.1038/s41467-018-04926-x

Methodologies for in vitro and in vivo Evaluation of Efficacy of Antifungal and Antibiofilm Agents and Surface Coatings Against Fungal Biofilms.

Van Dijck P, Sjollema J, Cammue BPA, Lagrou K, Berman J, d’Enfert C,  Andes DR, Arendrup MC, Brakhage AA, Calderone R, Cantón E, Coenye T, Cos  P, Cowen LE, Edgerton M, Espinel-Ingroff A, Filler SG, Ghannoum M, Gow  NAR, Haas H, Jabra-Rizk MA, Johnson EM, Lockhart SR, Lopez-Ribot JL,  Maertens J, Munro CA, Nett JE, Nobile CJ, Pfaller MA, Ramage G, Sanglard  D, Sanguinetti M, Spriet I, Verweij PE, Warris A, Wauters J, Yeaman MR,  Zaat SAJ, and Thevissen K. Microbial Cell. 2018 June 14;5(7). doi: 10.15698/mic2018.07.638

Rapid Phenotypic and Genotypic Diversification After Exposure to the Oral Host Niche in Candida albicans.

Forche A, Cromie G, Gerstein A, Solis N, Pisithkul T, Srifa, W, Jeffery E, Abbey D, Filler S, Dudley A, and Berman J. GENETICS. 2018 May 3; 209(1). doi: 10.1534/genetics.118.301019